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・ Sphingomonas abikonensis
・ Sphingomonas adhaesiva
・ Sphingomonas aromaticivorans
・ Sphingomonas echinoides
・ Sphingomonas parapaucimobilis
・ Sphingomonas paucimobilis
・ Sphingomonas phyllosphaerae
・ Sphingomonas stygia
・ Sphingomonas trueperi
・ Sphingomonas wittichii
・ Sphingomonas yanoikuyae
・ Sphingomonas yunnanensis
・ Sphingomorpha
・ Sphingomyelin
・ Sphingomyelin deacylase
Sphingomyelin phosphodiesterase
・ Sphingomyelin phosphodiesterase 1
・ Sphingomyelin phosphodiesterase D
・ Sphingomyelin synthase
・ Sphingonaepiopsis
・ Sphingonaepiopsis ansorgei
・ Sphingonaepiopsis asiatica
・ Sphingonaepiopsis gorgoniades
・ Sphingonaepiopsis gurkoi
・ Sphingonaepiopsis kuldjaensis
・ Sphingonaepiopsis malgassica
・ Sphingonaepiopsis nana
・ Sphingonaepiopsis obscurus
・ Sphingonaepiopsis pumilio
・ Sphingopus


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Sphingomyelin phosphodiesterase : ウィキペディア英語版
Sphingomyelin phosphodiesterase

Sphingomyelin phosphodiesterase (, ''neutral sphingomyelinase'', ''sphingomyelinase'', ''SMase'') is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide. The activation of SMase has been suggested as a major route for the production of ceramide in response to cellular stresses.
==The Sphingomyelinase Family==

Currently, five types of SMase have been identified. These are classified according to their cation dependence and pH optima of action and are:
*Lysosomal Acid SMase
*Secreted zinc-dependent Acid SMase
*Magnesium-dependent Neutral SMase
*Magnesium-independent Neutral SMase
*Alkaline SMase
Of these, the lysosomal acidic SMase and the magnesium-dependent neutral SMase are considered major candidates for the production of ceramide in the cellular response to stress.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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